Correlation of gut microbiota composition with colon adenomatous polyps

Microbiota is a collection of microorganisms that live in the oral cavity, respiratory tract and intestine of multicellular organisms. Microbiota exerts numerous physiological and pathological effects on the organism in which it resides. Increasing attention has been directed to the host-microbiota interaction, which is highly relevant to the development of carcinogenesis. Changes in the composition of the microbiota along with dysbiosis have provided an unbalanced digestive habitat for the microbiota, which causes the production of abnormal metabolites. Adenomatous polyps are a common symptom of colorectal cancer, the second leading cause of cancer-related deaths worldwide. Understanding the relationship between gut microbiota composition and colon adenomatous polyps may be a non-invasive tool for effective diagnosis as well as reducing health care costs. In this review article, we try to briefly examine the relationship between intestinal microbiota and adenomatous polyps.